Can Botox Cure Depression?

Major depression is a common and serious disorder. Often, psychotherapy and antidepressants are ineffective, and many patients are resigned to daily suffering. More research is needed, but a growing body of study suggests that modifying facial expressions can positively influence mood.

Several recent studies have indicated that Botox (botulinum toxin A) treatments may offer relief to some sufferers. Specifically, many who have had their furrowed brows eliminated with Botox have reported an improvement in mood. But is it that the Botox treatments simply make people feel better about themselves, thus temporarily lifting their depression? Recent studies suggest that something else may be at work. It was found that patients who had both the motivation to improve their looks cosmetically and sought treatment specifically for depression saw surprising results.

Is there a correlation between the muscles of the face and the inner workings of the brain? In a recent study, ten patients who had ongoing major depression, were treated with Botox. After two months of Botox treatments, they were clinically reevaluated. Nine of the ten patients treated claimed they were no longer depressed. Only one patient experienced no change in mood. Researchers concluded that Botox treatments on frown lines may be an effective treatment for patients with major depression who have not responded to routine pharmacological and psychotherapeutic treatments. Again, more study is needed, but early results are promising.

According to Dr. Simon Ourian, Epione’s Medical Director: “Botox has been used safely and successfully for wrinkle therapy worldwide for nearly 20 years. Additionally, Botox has been shown to effectively treat migraine headaches and has FDA approval for treating hyperhidrosis. The results of these studies on Botox and depression are very exciting. I look forward to reviewing future data.”